Chemical Biology

Research Activity

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• Tuning activity of metalloproteins and incorporation of metal clusters in protein clefts to design novel bio-catalyst.

• Synthesis and characterization of hypoxia active metal-based small molecules having potential against various cancer cells.

• Designing magnetic metal clusters for therapeutics

• Synthetic molecules whose binding to DNA can be photonically controlled

• Design and synthesis of bioactive peptides having potential against various cancer cells

• Studying mechanism of amyloid aggregation related with Alzheimer's disease and their respective neurotoxicity

• Target (Nucleic acid)-assisted combinatorial synthesis.

• DNA mediated asymmetric synthesis.

• Design and synthesis of small molecules targeting G-quadruplex DNA as novel anticancer agents.

• Peptide based therapeutics, cancer nanomedicine, drug delivery, biomimetic chemistry, chemical biology, supramolecular chemistry, applied biomaterials, cancer biology, regenerative nanomedicine.